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Kazuhiko Takahashi Selected Research

Selenoprotein P

9/2014Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells.
1/2013Serum selenium and selenoprotein P in patients with silicosis.
1/2012Inverse correlation between serum levels of selenoprotein P and adiponectin in patients with type 2 diabetes.
6/2011Selenoprotein-P is down-regulated in prostate cancer, which results in lack of protection against oxidative damage.
11/2010A liver-derived secretory protein, selenoprotein P, causes insulin resistance.
2/2008Aberrant expression of selenoproteins in the progression of colorectal cancer.
5/2005Serum selenoprotein-P levels in patients with inflammatory bowel disease.
11/2004Selenoprotein P, as a predictor for evaluating gemcitabine resistance in human pancreatic cancer cells.
11/2002Characterization of selenoprotein P as a selenium supply protein.

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Kazuhiko Takahashi Research Topics

Disease

4Body Weight (Weight, Body)
01/2012 - 12/2002
3Insulin Resistance
09/2014 - 11/2010
3Type 2 Diabetes Mellitus (MODY)
09/2014 - 11/2010
3Neoplasms (Cancer)
06/2011 - 02/2008
2Obesity
09/2006 - 11/2003
2Osteoporosis
12/2005 - 04/2004
1Bronchitis
03/2021
1Airway Obstruction (Choking)
03/2021
1Asphyxia (Suffocation)
03/2021
1Silicosis
01/2013
1Hypoadiponectinemia
01/2012
1Carcinogenesis
06/2011
1Prostatic Neoplasms (Prostate Cancer)
06/2011
1Dry Eye Syndromes (Dry Eye Syndrome)
03/2010
1Colorectal Neoplasms (Colorectal Cancer)
02/2008
1Inflammation (Inflammations)
08/2007
1Epilepsy (Aura)
01/2007
1Diabetes Mellitus
09/2006
1Dehydration (Water Stress)
07/2006
1Osteoporotic Fractures
12/2005
1Atherosclerotic Plaque (Atheroma)
05/2005
1Carcinoma (Carcinomatosis)
05/2005
1Ulcerative Colitis
05/2005
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
05/2005
1Bacterial Infections (Bacterial Infection)
05/2005
1Atherosclerosis
05/2005
1Pancreatic Neoplasms (Pancreatic Cancer)
11/2004
1Confusion (Bewilderment)
10/2004
1Bone Resorption
04/2004
1Neuroblastoma
02/2004
1Myocardial Ischemia (Ischemic Heart Diseases)
03/2003
1Coronary Disease (Coronary Heart Disease)
03/2003
1Jaundice (Icterus)
12/2002
1Lymphoma (Lymphomas)
11/2002

Drug/Important Bio-Agent (IBA)

9Selenoprotein PIBA
09/2014 - 11/2002
5Proteins (Proteins, Gene)FDA Link
09/2014 - 02/2008
4Reactive Oxygen Species (Oxygen Radicals)IBA
06/2011 - 04/2004
3DNA (Deoxyribonucleic Acid)IBA
11/2010 - 11/2003
3Histamine H3 Receptors (Histamine H3 Receptor)IBA
09/2006 - 12/2002
2Glucose (Dextrose)FDA LinkGeneric
01/2012 - 11/2010
2Messenger RNA (mRNA)IBA
11/2010 - 11/2003
2Selenoproteins (Selenoprotein)IBA
02/2008 - 05/2005
2Glutathione PeroxidaseIBA
02/2008 - 11/2002
2AntioxidantsIBA
02/2008 - 12/2005
2thioperamideIBA
09/2006 - 07/2006
2Histamine (Histamine Dihydrochloride)FDA Link
09/2006 - 12/2002
2CytokinesIBA
05/2005 - 04/2004
1PlasticsIBA
03/2021
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2014
1SeleniumIBA
01/2013
1AdiponectinIBA
01/2012
1Free RadicalsIBA
06/2011
1Ophthalmic Solutions (Eye Drops)IBA
03/2010
1Thioredoxin-Disulfide ReductaseIBA
02/2008
1Glutathione (Reduced Glutathione)IBA
02/2008
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
02/2008
1Pharmaceutical PreparationsIBA
02/2008
1Platelet Activating FactorIBA
02/2008
1ProstaglandinsIBA
08/2007
1Biological ProductsIBA
08/2007
1Protein Isoforms (Isoforms)IBA
08/2007
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2007
1Carbapenems (Carbapenem Antibiotics)IBA
01/2007
1panipenemIBA
01/2007
1Valproic Acid (Depakote)FDA LinkGeneric
01/2007
1Meropenem (Merrem)FDA LinkGeneric
01/2007
1ImipenemFDA Link
01/2007
1imetitIBA
09/2006
1LigandsIBA
09/2006
1Angiotensin IIIBA
07/2006
1imidazoleIBA
05/2006
1Vitamin K 2 (Vitamin K2)IBA
12/2005
1menatetrenoneIBA
12/2005
1CoffeeFDA Link
05/2005
1HomocysteineIBA
05/2005
1CholesterolIBA
05/2005
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2005
1Oxygen (Dioxygen)IBA
05/2005
1Interleukin-6 (Interleukin 6)IBA
05/2005
1GemcitabineFDA Link
11/2004
1Retroelements (Retrotransposon)IBA
10/2004
1Alkaline PhosphataseIBA
04/2004
1OsteocalcinIBA
04/2004
1Hormones (Hormone)IBA
04/2004
1deoxypyridinolineIBA
04/2004
1OsteopontinIBA
04/2004
1Transforming Growth Factor beta1 (TGF beta 1)IBA
04/2004
1Small Interfering RNA (siRNA)IBA
02/2004
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
02/2004
1Neuropeptide YIBA
11/2003
1DobutamineFDA LinkGeneric
03/2003
1Dipyridamole (Persantine)FDA LinkGeneric
03/2003
1quinolineIBA
12/2002
1Blood Proteins (Serum Proteins)IBA
11/2002

Therapy/Procedure

1Tracheotomy
03/2021
1Combined Modality Therapy
03/2021
1Ovariectomy (Oophorectomy)
12/2005